Yes, this supplement is manufactured in the United States using the safest, strictest manufacturing guidelines and only contains safe, beneficial, natural ingredients. It is also soy-free, gluten-free, milk-free, wheat-free, egg-free, GMO-free, peanut-free, shellfish-free, and sugar and sweetener-free. To further increase safety, we advise all users to show a bottle to their doctor to ensure compatibility with other medications and treatments.